Gene Therapy for Age-Related Macular Degeneration
نویسندگان
چکیده
منابع مشابه
Radiation therapy for age-related macular degeneration.
Neovascular age-related macular degeneration is the most common cause of severe irreversible blindness in the Western world in people older than age 50. Laser photocoagulation is the only proven treatment for this disease; however, fewer than 20% of patients are eligible for this treatment because the majority of choroidal neovascularization membranes are not visible by ophthalmoscopy or angiog...
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Background & Aims: To investigate the association of CFI p.Gly119Arg polymorphism with Age-related macular degeneration (AMD). Materials & Methods: In this case-control study, the association of p.Gly119Arg polymorphism in CFI gene was investigated in 65 patients suffering from AMD and150 healthy age, sex and ethnicity matched unrelated people as control group. Both of the case and cont...
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Stargardt disease is a recessively inherited degeneration of the macula of the retina arising in youth (usually in teenagers and young adults) that is caused by defects in the ABCR gene (1). Rando Allikmets et al. investigate (2) the idea that heterozygote carriers of ABCR mutations might develop age-related macular degeneration (AMD) late in life. We wish to point out methodological deficienci...
متن کاملبررسی اثر چندشکلی ژنتیکی xrcc7 با ریسک ابتلا به بیماریamd age-related macular degeneration))
amd بیماری تحلیل شبکیه است که عامل اصلی کوری در افراد بالای 55 سال در جهان غرب به شمار می-رود. در اثر این بیماری، لیپوپروتئین ها در شبکیه تجمع پیدا کرده و رگ زایی القاء می شود. ثابت شده است که عوامل ژنوتوکسیک محیطی مثل سیگار کشیدن، رژیم غذایی و نور در افراد پیر با زمینه ی ژنتیکی مستعد در بروز بیماری دخیل می باشند. بنابراین ما یک مطالعه ی مـورد- شاهـدی را ترتیب دادیم که شـامل 112 فرد مبتلا به am...
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ژورنال
عنوان ژورنال: Asia-Pacific Journal of Ophthalmology
سال: 2016
ISSN: 2162-0989
DOI: 10.1097/apo.0000000000000222